networkpharmacology相关论文
Safety and efficacy of Compound Huangdai Tablets combined with all-trans retinoic acid for treatment
Objective:To evaluate the safety and efficacy of Compound Huangdai Tablets(Realgar-Indigo Naturalis formula,RIF)combined......
脑缺血(cerebral ischemia,CI)具有高发病率、高致畸率,是全球第二大致死疾病.中药(traditional Chinese medicine,TCM)益气活血方......
Transcriptional profiling and network pharmacology analysis identify the potential biomarkers from C
Huosu Yangwei (HSYW) Formula is a traditioanl Chinese herbal medicine that has been extensively used to treat chronic at......
Bladder cancer is the most common malignancy of the urinary system.Compound Kushen Injection (CKI) is a Chinese medicina......
Xinglou Chengqi Decoction improves neurological function in experimental stroke mice as evidenced by
The current study was designed to explore the brain protection mechanism of Xinglou Chengqi Decoction (XCD)based on gut ......
The infiltration of immune cells into the hepatocellular carcinoma microenvironment is the main reason why hepatocel-lul......
目标探讨乌头汤中川乌与黄芪的增效作用及甘草联合川乌减毒作用的机制,阐明乌头汤的配伍原则.方法通过中药系统药理学数据库及分析......
目的:基于数据挖掘和网络药理学方法，探究贾跃进老中医临床治疗抑郁症的核心组方及其作用机制。方法:收集2016年1月1日－2020年7月1日......
Molecular mechanism of treatment of pneumonia in children with Mori cortex - Lycii cortex based on n
Objective: To study the molecular mechanism of Mori Cortex - Lycii Cortex for infantile pneumonia based on network pharm......
Elucidation of the hepatoprotective effect and mechanism of Melastoma dodecandrum Lour.based on netw
Objective:To systematically explore the effect and mechanism of melastomatis dodecandri herba(Melastoma dodecandrum Lour......
Objective: This article uses the method of network pharmacology to study the related mechanism of Guilu Erxian Gum in th......
Objective: This study was designed to evaluate the hypolipidemic activity of Brassica rapa and explore its mechanism by ......
Objective: To study the potential therapeutic effect of Yigan Powder on Alzheimer\'s disease (AD) comorbid Depressive ......
Mechanism of “Pinelliae rhizoma-Arisaematis rhizoma” in treatment of lung cancer based on network ph
Objective: The study was designed to explore the mechanism of “Pinelliae Rhizoma- Arisaematis Rhizoma” (PR-AP) in trea......
Objective: The mechanism of Yupingfeng Powder in the treatment of non-small cell lung cancer was analyzed by network pha......
目的:采用网络药理学方法探究左归丸对治疗骨质疏松的有效活性成分、作用靶点和潜在分子机制.方法:利用TC-MSP数据库预测左归丸活......
目的 采用网络药理学和血清代谢组学相结合的方法,探讨复方阿胶浆(FFEJJ)治疗再生障碍性贫血(AA)潜在作用机制.方法 从中药系统药......
Target prediction and activity verification for the antidepressant ac-tion of Huangqin (Radix Scutel
OBJECTIVE:To decipher the antidepressant targets and mechanisms of Huangqin (Radix Scutellariae Baicalensis) (RSB) by a ......
目的:基于网络药理学分析左金丸治疗胃食管反流病的作用机制。方法:通过TCMSP检索左金丸的有效成分及蛋白靶点，在Uniprot数据库中将......
Study on the mechanism of Salvia miltiorrhiza-Pueraria lobata in the treatment of type 2 diabetes me
Objective: To explore the synergistic mechanism of salvia miltiorrhiza and Pueraria lobata of multi-component, multi-tar......
Study on the mechanism of two related Chinese herbs Chenpi-Banxia in the treatment of coronary micro
Objective: By the method of network pharmacology to study the main active compounds,main target genes,critical path and ......
Exploring the anti-diabetic effects and the underlying mechanisms of ethyl acetate extract from Soph
Background: Sophora flavescens, a traditional Chinese herb medicine, has been used to prevent and cure type 2 diabetes m......
Potential molecular mechanism of Euonymus alatus in the treatment of type 2 diabetes based on networ
Objective: To investigate the potential molecular mechanism of Guijianyu(Euonymus Alatus) in the treatment of type 2 dia......
本研究通过网络药理学方法,探讨丹参治疗病理性瘢痕(pathological scar,PS)的作用机制.通过TCMSP数据库筛选丹参的活性成分和药物......
采用网络药理学方法探讨附子汤治疗慢性心力衰竭的作用机制.首先利用SymMap数据库分析各味药的现代医学症状,然后通过TCMSP、ETCM......
Danshen-Chuanxiongqin Injection(DCI)is a commonly used traditional Chinese medicine for the treatment of cereb-ral ische......
Protective mechanisms of Agrimonia pilosa Ledeb in dextran sodium sulfate-induced colitis as determi
Previous studies reported that Agrimonia pilosa (AP) Ledeb possessed diverse biological activi-ties,including anti-infla......
A Network Pharmacology Study to Uncover the Multiple Molecular Mechanism of the Chinese Patent Medic
Since the outbreak of the novel corona virus disease 2019 (COVID-19) at the end of 2019,specific antiviral drugs have be......
Network Pharmacology in Research of Chinese Medicine Formula: Methodology, Application and Prospecti
Chinese medicine (CM) is usually prescribed as CM formula to treat disease.The lack of effective research approach makes......
Design of new traditional Chinese medicine herbal formulae for treatment of type 2 diabetes mellitus
In the present study,28 Chinese medicinal herbs belonging to traditional Chinese medicine (TCM) for the treatment of typ......
Network pharmacology-based analysis of Chinese herbal Naodesheng formula for application to Alzheime
Naodesheng (NDS) formula,which consists of Rhizoma Chuanxiong,Lobed Kudzuvine,Carthamus tinctorius,Radix Notoginseng,and......
A novel approach based on metabolomics coupled with network pharmacology to explain the effect mecha
Danggui Buxue Tang (DBT) is a famous Chinese medicinal decoction.Mechanism of DBT action is wide ranging and unclear.Exp......
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Revealing the synergistic mechanism of Shenfu Decoction for anti-heart failure through network pharm
The present study was designed to investigate the targets and synergistic mechanism of Shenfu Decoction (SFD) in the tre......
Cynanchum paniculatum and its Major Active Constitutes for Inflammatory Related Diseases and Tumor M
Objective Cynanchum paniculatum Radix,known as Xuchangqing in Chinese,is commonly used in Traditional Chinese Medicine(T......
Study on the multi-targets mechanism of YiQiFuMai powder injection on cardio-cerebral ischemic disea
Aim YiQiFuMai Powder Injection is a wellknown traditional Chinese medicine formula that has been used extensively in cli......
Computational prediction of drug-target interactions(DTIs)and drug repositioning provide low cost and high efficient way......
Aim: Advances in systems biology suggest that network pharmacology may be a novel and more effective strategy for drug d......
Tanshinone IIA(Tan IIA)the major component of traditional Chinese medicinal herb Danshen,give its anti-cancer effects pa......
Quantitative identification of compounds-dependent on-modules and differential allosteric modules fr
Module-based methods have made much progress in deconstructing biological networks.However, it is a great challenge to q......
Network pharmacology-based analysis of Chinese herbal NaoDeSheng formula for application to Alzheime
OBJECTIVE To predict the potential targets and uncover the mechanisms of NaoDeSheng formula for the treatment of Alzheim......
Novel network pharmacology methods for drug mechanism of action identification,pre-clinical drug scr
The high rates of failure in oncology drug clinical trials highlight the problems of using pre-clinical data to predict ......
Explore the relationship between lung cancer and genes and other influence based on network pharmaco
Objective: To filter the genes related to lung cancer by network pharmacology and to discuss the relationship with lung ......
Revealing the combination principles of herbal pair Euphorbia kansui and Glycyrrhiza used in the the
BACKGROUND: Although herbal pair Euphorbia kansui (GS)/Glycyrrhiza (GC) is one of the so-called "Eighteen antagonistic ......
Network-based virtual screening of active ingredients in Chinese herbal formulae for the treatment o
Objectives: This research aims to construct and analyze chemical ingredients network of herbal formulae, and provide pot......
Network pharmacology approach to predicting the anti-cancer active ingredients of Ganfule, a Chinese
Ethmopharmcology relevance: Ganfule(GFL),one of herbal medicines formula in china, has been widely used as the preventio......
Insights into the mechanism of Huangqi decoction(HQD)by means of metabolomics and network pharmacolo
Huangqi decoction(HQD)consists of Radix Astragali(RA)and Radix Glycyrrhizae(RG)in a ratio of 6:1,which has been used to ......
Study on the mechanism of Wenyang Jieyu Granules in the treatment of depression based on network pha
Objective: To explore the potential antidepressant mechanism of Wenyang Jieyu Granules with multiple targets and compone......
